(question from a test) Protein SUMOylation can have a large variety of functions (whereas the proteossome goes to degradation, SUMOylation has many more characteristics)

(question from a test) Protein SUMOylation can have a large variety of functions (whereas the proteossome goes to degradation, SUMOylation has many more characteristics). a) Identify 3 of these functions. b) Explain how can the same modification have such diverse functions? Transcribed Image Text: Signaling functions of SUMO
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Higher-order
chromatin structure
Differential
Antagonism
of ubiquitination
protein-protein
interaction
Sumo
Nuclear pore
complex shuttling
Substrate
Subcellular
localization
Integrity of PML
nuclear bodies
Transcription
factor activity
Regulation
of DNA binding Transcribed Image Text: SUMO E1, E2, E3 enzymes, ATP
SUMO
Target
Target
Isopeptidases
b
Partner A
SUMO
SUMO
Target
Target
Target
Partner B

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